Association of a locus on rat chromosome 4 with anxiety-related behaviors in two selectively bred rat lines
نویسندگان
چکیده
منابع مشابه
Behavioural profiles of two Wistar rat lines selectively bred for high or low anxiety-related behaviour.
Over the past years, two breeding lines, derived originally from outbred Wistar rats, have been established that differ markedly and consistently in their anxiety-related behaviour in the elevated plus-maze. At the age of ten weeks, rats were tested once on the elevated plus-maze and the males and females displaying the most anxious and the least anxious behaviour were sib-mated to start a new ...
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In humans, there is unequivocal evidence of an association between anxiety states and altered respiratory function. Despite this, the link between anxiety and respiration has been poorly evaluated in experimental animals. The primary objective of the present study was to investigate the hypothesis that genetic lines of rats that differ largely in their anxiety level would display matching alter...
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ژورنال
عنوان ژورنال: Genetics and Molecular Biology
سال: 2008
ISSN: 1415-4757
DOI: 10.1590/s1415-47572008000500008